Accuracy of fetal gender determination by analysis of DNA in maternal plasma.

نویسندگان

  • A Sekizawa
  • T Kondo
  • M Iwasaki
  • A Watanabe
  • M Jimbo
  • H Saito
  • T Okai
چکیده

J Chromatogr 1984;311:291–9. 3. Chen Y, Potter JM, Ravenscroft PJ. A quick, sensitive high-performance liquid chromatography assay for monoethylglycinexylidide and lignocaine in serum/plasma using solid-phase extraction. Ther Drug Monit 1992;14:317– 21. 4. Willis CR, Greenblatt DJ, Benjamin DM, Abernethy DR. Simultaneous determination of lidocaine and its deethylated metabolites using gas-liquid chromatography with nitrogen-phosphorus detection. J Chromatogr 1984; 307:200–5. 5. Lorec AM, Bruguerolle B, Attolini L, Roucoules X. Rapid simultaneous determination of lidocaine, bupivacaine, and their two main metabolites using capillary gas-liquid chromatography with nitrogen phosphorus detector. Ther Drug Monit 1994;16:592–5. 6. Oellerich M, Burdelski M, Lautz HU, Binder L, Pichlmayr R. Predictors of one-year pretransplant survival in patients with cirrhosis. Hepatology 1991; 14:1029–34. 7. Shiffman ML, Luketic VA, Sanyal AJ, Thompson EB. Use of hepatic lidocaine metabolism to monitor patients with chronic liver disease. Ther Drug Monit 1996;18:372–7. 8. Burdelski M, Schutz E, Nolte-Buchholtz S, Armstrong VW, Oellerich M. Prognostic value of the monoethylglycinexylidide test in pediatric liver transplant candidates. Ther Drug Monit 1996;18:378–82. 9. Andreeva M, Niedmann PD, Schutz E, Wieland E, Armstrong VW, Oellerich M. Determination of MEGX by HPLC with fluorescence detection. Clin Chem 1997;43:1081–3. 10. Laroche N, Leneveu A, Roux A, Flouvat B. Capillary gas chromatographic method for the measurement of small concentrations of monoethylglycinexylidide and lidocaine in plasma. J Chromatogr B Biomed Sci Appl 1998; 716:375–81. 11. Schutz E, Shipkova M, Armstrong VW, Oellerich M. Monoethylglycinexylidide (MEGX) liver function test is not compromised by 3-hydroxy MEGX in humans. Hepatology 1998;28:1439–40. 12. Leclercq I, Saliez A, Wallemacq PE, Horsmans Y, Lambotte L. The monoethylglycinexylidide test does not correctly evaluate lidocaine metabolism after ischemic liver injury in the rat. Hepatology 1997;26:1182–8.

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منابع مشابه

An Effective Method for Detecting Y-chromosome Specific Sequences of Circulating Fetal DNA in Maternal Plasma During the First-trimester

Background and Aims: New advances in the use of cell-free fetal DNA (cffDNA) in maternal plasma of pregnant women has provided the possibility of applying cffDNA in prenatal diagnosis as a non-invasive method. One of the applications of prenatal diagnosis is fetal gender determination. Early prenatal determination of fetal sex is required for pregnant women at risk of X-linked and some endocrin...

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O-45: Quantification of Cell-Free-Fetal-DNAfrom Maternal Plasma for the First Time in Pakistan:Implications for Non-Invasive PrenatalDiagnosis of Genetic Disorders

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O-45: Quantification of Cell-Free-Fetal-DNAfrom Maternal Plasma for the First Time in Pakistan:Diagnosis of Genetic Disorders

Background: Current prenatal diagnosis requires invasive testing which carries a 1-4% procedure-related-risk of miscarriage; hence, non-invasive techniques are desired. The recent demonstration of cell-free-fetal-DNA enriched from maternal plasma has opened new possibilities for non-invasive-prenatal-diagnosis of not only genetic-disorders such as β-thalassaemia and haemophilia but also chromos...

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P-211: Quantitative Changes of Fetal DNA in Maternal Circulation during Pregnancy Based on Detection of SRY Gene in Ovine Species

Background: It is well documented that fetal DNA can cross the placenta and is present in peripheral maternal blood during pregnancy in human. This fetal DNA also named circulating cell free fetal DNA, has emerged as a valuable source for genetic evaluation. Compared with humans, ovine species have a different structure of placental (synepitheliochorial) with no direct contact between the troph...

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Multiplex PCR for 17 Y-Chromosome Specific Short Tandem Repeats (STR) to Enhance the Reliability of Fetal Sex Determination in Maternal Plasma

The aim of the study was to demonstrate the influence of target gene and amplification product length on the performance of fetal gender determination systems using maternal plasma. A total of 40 pairs of plasma DNA samples from pregnant women and genomic DNA samples from maternal blood, amniotic fluid and paternal blood were isolated for gender determination by amplification of the amelogenin ...

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عنوان ژورنال:
  • Clinical chemistry

دوره 47 10  شماره 

صفحات  -

تاریخ انتشار 2001